Publications

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2017

Juan Wang, Shasha Zhao, Wei He, Yun Wei, Yang Zhang, Henry Pegg, Paul Shore, Stefan GE Roberts, and Wensheng Deng. A Transcription Factor IIA Binding Site Differentially Regulates RNA Polymerase II-Mediated Transcription in a Promoter Context-dependent Manner. J. Biol. Chem. jbc.M116.770412. doi:10.1074/jbc.M116.770412 in press

Rooney N, Riggio AI, Mendoza-Villanueva D, Shore P, Cameron ER, Blyth K. Runx Genes in Breast Cancer and the Mammary Lineage.Adv Exp Med Biol. 2017;962:353-368. doi: 10.1007/978-981-10-3233-2_22. PMID:28299668

2016

Juan Wang, Shasha Zhao, Yun Wei, Ying Zhou, Paul Shore2# and Wensheng Deng1# (2016). Cytoskeletal filamin A differentially modulates RNA polymerase III gene transcription in transformed cell lines. J. Biol Chem, ePub. http://www.jbc.org/cgi/doi/10.1074/jbc.M116.735886. 2016 #Co-corresponding authors

2014

Owens TW, Rogers RL, Best S, Ledger A, Mooney AM, Ferguson A, Shore P, Swarbrick A, Ormandy CJ, Simpson PT, Carroll JS, Visvader JE, Naylor MJ. Runx2 is a novel regulator of mammary epithelial cell fate in development and breast cancer. Cancer Res. 2014 Jul 23. pii: canres.0053.2014. [Epub ahead of print]

2012

Toska E, Campbell HA, Shandilya J, Goodfellow SJ, Shore P, Medler KF, Roberts SG. (In-press). Repression of Transcription by WT1-BASP1 Requires the Myristoylation of BASP1 and the PIP2-Dependent Recruitment of Histone Deacetylase. Cell Reports, 2(3), 462. eScholarID:168229 | DOI:10.1016/j.celrep.2012.08.005

Wensheng Deng, Cesar Lopez-Camacho, Jen-Yang Tang, Daniel Mendoza-Villanueva, Apolinar Maya-Mendoza, Dean A. Jackson, and Paul Shore. (2012). Cytoskeletal protein filamin A is a nucleolar protein that suppresses ribosomal RNA gene transcription. Proceedings of the National Academy of Sciences of the United States of America, 109(5), 1524. eScholarID:153106 | DOI:10.1073/pnas.1107879109

2011

Mendoza-Villanueva, D., Zeef, L. & Shore, P (2011). Metastatic breast cancer cells inhibit osteoblast differentiation through the Runx2/CBFβ-dependent expression of the Wnt antagonist, sclerostin. Breast cancer research : BCR, 13(5), R106. eScholarID:134983 | PMID:22032690 | DOI:10.1186/bcr3048

Ann, E., Kim, H., Choi, Y., Kim, M., Mo, J., Jung, J., Yoon, J., Kim, S., Moon, J., Seo, M., Hong, J., Jang, W., Shore, P., Komori, T., Koh, J. & Park, H (2011). Inhibition of Notch1 signaling by Runx2 during osteoblast differentiation. J Bone Miner Res, 26(2), 317-30. eScholarID:117090 | PMID:20740684 | DOI:10.1002/jbmr.227

2010

Mendoza-Villanueva D, Deng W, Lopez-Camacho C, Shore P. (2010). The Runx transcriptional co-activator, CBFbeta, is essential for invasion of breast cancer cells. Molecular Cancer, 9(171), eScholarID:117083 | DOI:10.1186/1476-4598-9-171

2009

Little HJ, Rorick NK, Su LI, Baldock C, Malhotra S, Jowitt T, Gakhar L, Subramanian R, Schutte BC, Dixon MJ, Shore P. (2009). Missense mutations that cause Van der Woude syndrome and popliteal pterygium syndrome affect the DNA-binding and transcriptional activation functions of IRF6. Human Molecular Genetics, 18(3), 535-545. eScholarID:1c8078 | DOI:10.1093/hmg/ddn381

2006

Richardson RJ, Dixon J, Malhotra S, Hardman MJ, Knowles L, Boot-Handford RP, Shore P, Whitmarsh A, Dixon MJ. (2006). Irf6 is a key determinant of the keratinocyte proliferation-differentiation switch.Nature Genetics, 38(11), 1329-1334. eScholarID:68278 | DOI:10.1038/ng1894

2005

Shore P. (2005). A role for Runx2 in normal mammary gland and breast cancer bone metastasis.Journal of cellular biochemistry, 96(3), 484-9. eScholarID:1c5347 | PMID:16052475 | DOI:10.1002/jcb.20557

Inman CK, Li N, Shore P. (2005). Oct-1 counteracts autoinhibition of Runx2 DNA binding to form a novel Runx2/Oct-1 complex on the promoter of the mammary gland-specific gene beta-casein.Molecular and cellular biology, 25(8), 3182-93. eScholarID:1c5346 | PMID:15798204 | DOI:10.1128/MCB.25.8.3182-3193.2005

2003

Inman CK, Shore P. (2003). The osteoblast transcription factor Runx2 is expressed in mammary epithelial cells and mediates osteopontin expression. J Biol Chem, 278(49), 48684-9. eScholarID:1c1912 | PMID:14506237 | DOI:10.1074/jbc.M308001200

Bristow CA, Shore P. (2003). Transcriptional regulation of the human MIP-1alpha promoter by RUNX1 and MOZ. Nucleic acids research, 31(11), 2735-44. eScholarID:1c1913 | PMID:12771199 | DOI:10.1093/nar/gkg401

2002

Shore P, Dietrich W, Corcoran LM. (2002). Oct-2 regulates CD36 gene expression via a consensus octamer, which excludes the co-activator OBF-1. Nucleic acids research, 30(8), 1767-73. eScholarID:1c1914 | PMID:11937630 | DOI:10.1093/nar/30.8.1767

2001

Bouillet P, Zhang LC, Huang DC, Webb GC, Bottema CD, Shore P, Eyre HJ, Sutherland GR, Adams JM. (2001). Gene structure alternative splicing, and chromosomal localization of pro-apoptotic Bcl-2 relative Bim. Mammalian genome : official journal of the International Mammalian Genome Society, 12(2), 163-8. eScholarID:1c3435 | PMID:11210187 | DOI:10.1007/s003350010242

2000

Shore P. and Sharrocks A.D. (2000). Regulation of Transcription by Extracellular Signals. In J. Locker (Ed.), Transcription Factors. (pp. 10). Bios Scientific Ltd. eScholarID:3c250

Corcoran, LM and SHORE P. (2000). Transcription Factors in B-Cell Development and Function. The Immunologist, 8, 11-13. eScholarID:1c6589

1999

Yang SH, Shore P, Willingham N, Lakey JH, Sharrocks AD. (1999). The mechanism of phosphorylation-inducible activation of the ETS-domain transcription factor Elk-1. The EMBO journal, 18(20), 5666-74. eScholarID:1c3436 | PMID:10523309 | DOI:10.1093/emboj/18.20.5666

1997

West AG, Shore P, Sharrocks AD. (1997). DNA binding by MADS-box transcription factors: a molecular mechanism for differential DNA bending. Molecular and cellular biology, 17(5), 2876-87. eScholarID:1c3437 | PMID:9111360

1996

Shore P, Whitmarsh AJ, Bhaskaran R, Davis RJ, Waltho JP, Sharrocks AD. (1996). Determinants of DNA-binding specificity of ETS-domain transcription factors. Molecular and cellular biology, 16(7), 3338-49. eScholarID:1c3438 | PMID:8668149

1995

Shore P, Sharrocks AD. (1995). The ETS-domain transcription factors Elk-1 and SAP-1 exhibit differential DNA binding specificities. Nucleic acids research, 23(22), 4698-706. eScholarID:1c3439 | PMID:8524663 | DOI:10.1093/nar/23.22.4698

Whitmarsh AJ, Shore P, Sharrocks AD, Davis RJ. (1995). Integration of MAP kinase signal transduction pathways at the serum response element. Science, 269(5222), 403-7. eScholarID:1c3440 | PMID:7618106 | DOI:10.1126/science.7618106

Sharrocks AD, Shore P. (1995). DNA bending in the ternary nucleoprotein complex at the c-fos promoter. Nucleic acids research, 23(13), 2442-9. eScholarID:1c3441 | PMID:7630721 | DOI:10.1093/nar/23.13.2442

Shore P, Sharrocks AD. (1995). The MADS-box family of transcription factors. European journal of biochemistry / FEBS, 229(1), 1-13. eScholarID:1c3442 | PMID:7744019 | DOI:10.1111/j.1432-1033.1995.tb20430.x

Shore P, Bisset L, Lakey J, Waltho JP, Virden R, Sharrocks AD. (1995). Characterization of the Elk-1 ETS DNA-binding domain. Journal of Biological Chemistry, 270(11), 5805-11. eScholarID:1c3443 | PMID:7890710

Shore P., Sharrocks A.D. Turning On Genes. Trends in Biochemical Sciences, 20,  7,  257-293 1995.

1994

Shore P, Sharrocks AD. (1994). The transcription factors Elk-1 and serum response factor interact by direct protein-protein contacts mediated by a short region of Elk-1. Molecular and cellular biology, 14(5), 3283-91. eScholarID:1c3444 PMID:8164681

Hornby DP, Whitmarsh A, Pinarbasi H, Kelly SM, Price NC, Shore P, Baldwin GS, Waltho J. (1994). The DNA recognition subunit of a DNA methyltransferase is predominantly a molten globule in the absence of DNA. FEBS letters, 355(1), 57-60. eScholarID:1c5753 | PMID:7957963 | DOI:10.1016/0014-5793(94)01171-0

1992

D Hornby, K Ford, P Shore. Purification of DNA Binding Proteins by Affinity and Ion Exchange Chromatography. Practical Protein Chromatography, 273-286. (1992)