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Dr Paul Shore's Research and Teaching

Gene expression and human disease

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Day: 25 April 2014

Apr 25

Repression of Transcription by WT1-BASP1 Requires the Myristoylation of BASP1 and the PIP2-Dependent Recruitment of Histone Deacetylase

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      Repression of Transcription by WT1-BASP1 Requires the Myristoylation of BASP1 and the PIP2-Dependent Recruitment of Histone Deacetylase.

Shore Laboratory – Manchester University

Our latest research paper published in the Nature journal, Oncogene (Impact Factor 7.971). Ran, R., Harrison, H., Syamimi Ariffin, N. et al. A role for CBFβ in maintaining the metastatic phenotype of breast cancer cells. Oncogene 39, 2624–2637 (2020).

  • Runx2 Is a Novel Regulator of Mammary Epithelial Cell Fate in Development and Breast Cancer
  • Repression of Transcription by WT1-BASP1 Requires the Myristoylation of BASP1 and the PIP2-Dependent Recruitment of Histone Deacetylase
  • Find A PhD Project: The molecular basis of metastatic Breast Cancer at University of Manchester
  • Cytoskeletal protein filamin A is a nucleolar protein that suppresses ribosomal RNA gene transcription. – F1000Prime
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