2020
Ran Ran, Hannah Harrison, Nur Syamimi Ariffin, Rahna Ayub, Henry J. Pegg, Wensheng Deng, Andrea Mastro, Penny D. Ottewell, Susan M. Mason, Karen Blyth, Ingunn Holen & Paul Shore. A role for CBFβ in maintaining the metastatic phenotype of breast cancer cells. (2020) Oncogene. 2020 Jan 31. doi: 10.1038/s41388-020-1170-2. [Epub ahead of print]
Feixia Peng, Ying Zhou, Juan Wang, Baoqiang Guo, Yun Wei, Huan Deng, Zihui Wu, Cheng Zhang, Kaituo Shi, Yuan Li, Xin Wang, Paul Shore, Shasha Zhao and Wensheng Deng. (2020). The transcription factor Sp1 modulates RNA polymerase Ⅲ gene transcription by controlling BRF1 and GTF3C2 expression in human cells. The Journal of Biological Chemistry 295, 4617-4630. doi: 10.1074/jbc.RA119.011555
2019
Pegg HJ, Harrison H, Rogerson C, Shore. The RUNX Transcriptional Coregulator, CBFβ, Suppresses Migration of ER+ Breast Cancer Cells by Repressing ERα-Mediated Expression of the Migratory Factor TFF1. (2019) Mol. Cancer Res. doi: 10.1158/1541-7786.MCR-18-1039
2018
Harrison H, Henry J. Pegg, Jamie Thompson, Christian Bates and Paul Shore HIF1-alpha expressing cells induce a hypoxic-like response in neighbouring cancer cells. (2018) BMC Cancer 18:674 doi: 10.1186/s12885-018-4577-1
2017
Juan Wang, Shasha Zhao, Wei He, Yun Wei, Yang Zhang, Henry Pegg, Paul Shore, Stefan GE Roberts, and Wensheng Deng. A Transcription Factor IIA Binding Site Differentially Regulates RNA Polymerase II-Mediated Transcription in a Promoter Context-dependent Manner. J. Biol. Chem. jbc.M116.770412. doi:10.1074/jbc.M116.770412 in press
Rooney N, Riggio AI, Mendoza-Villanueva D, Shore P, Cameron ER, Blyth K. Runx Genes in Breast Cancer and the Mammary Lineage.Adv Exp Med Biol. 2017;962:353-368. doi: 10.1007/978-981-10-3233-2_22. PMID:28299668
2016
Juan Wang, Shasha Zhao, Yun Wei, Ying Zhou, Paul Shore2# and Wensheng Deng1# (2016). Cytoskeletal filamin A differentially modulates RNA polymerase III gene transcription in transformed cell lines. J. Biol Chem, ePub. http://www.jbc.org/cgi/doi/10.1074/jbc.M116.735886. 2016 #Co-corresponding authors
2014
Owens TW, Rogers RL, Best S, Ledger A, Mooney AM, Ferguson A, Shore P, Swarbrick A, Ormandy CJ, Simpson PT, Carroll JS, Visvader JE, Naylor MJ. Runx2 is a novel regulator of mammary epithelial cell fate in development and breast cancer. Cancer Res. 2014 Jul 23. pii: canres.0053.2014. [Epub ahead of print]
2012
Toska E, Campbell HA, Shandilya J, Goodfellow SJ, Shore P, Medler KF, Roberts SG. (In-press). Repression of Transcription by WT1-BASP1 Requires the Myristoylation of BASP1 and the PIP2-Dependent Recruitment of Histone Deacetylase. Cell Reports, 2(3), 462. eScholarID:168229 | DOI:10.1016/j.celrep.2012.08.005
Wensheng Deng, Cesar Lopez-Camacho, Jen-Yang Tang, Daniel Mendoza-Villanueva, Apolinar Maya-Mendoza, Dean A. Jackson, and Paul Shore. (2012). Cytoskeletal protein filamin A is a nucleolar protein that suppresses ribosomal RNA gene transcription. Proceedings of the National Academy of Sciences of the United States of America, 109(5), 1524. eScholarID:153106 | DOI:10.1073/pnas.1107879109
2011
Mendoza-Villanueva, D., Zeef, L. & Shore, P (2011). Metastatic breast cancer cells inhibit osteoblast differentiation through the Runx2/CBFβ-dependent expression of the Wnt antagonist, sclerostin. Breast cancer research : BCR, 13(5), R106. eScholarID:134983 | PMID:22032690 | DOI:10.1186/bcr3048
Ann, E., Kim, H., Choi, Y., Kim, M., Mo, J., Jung, J., Yoon, J., Kim, S., Moon, J., Seo, M., Hong, J., Jang, W., Shore, P., Komori, T., Koh, J. & Park, H (2011). Inhibition of Notch1 signaling by Runx2 during osteoblast differentiation. J Bone Miner Res, 26(2), 317-30. eScholarID:117090 | PMID:20740684 | DOI:10.1002/jbmr.227
2010
Mendoza-Villanueva D, Deng W, Lopez-Camacho C, Shore P. (2010). The Runx transcriptional co-activator, CBFbeta, is essential for invasion of breast cancer cells. Molecular Cancer, 9(171), eScholarID:117083 | DOI:10.1186/1476-4598-9-171
2009
Little HJ, Rorick NK, Su LI, Baldock C, Malhotra S, Jowitt T, Gakhar L, Subramanian R, Schutte BC, Dixon MJ, Shore P. (2009). Missense mutations that cause Van der Woude syndrome and popliteal pterygium syndrome affect the DNA-binding and transcriptional activation functions of IRF6. Human Molecular Genetics, 18(3), 535-545. eScholarID:1c8078 | DOI:10.1093/hmg/ddn381
2006
Richardson RJ, Dixon J, Malhotra S, Hardman MJ, Knowles L, Boot-Handford RP, Shore P, Whitmarsh A, Dixon MJ. (2006). Irf6 is a key determinant of the keratinocyte proliferation-differentiation switch.Nature Genetics, 38(11), 1329-1334. eScholarID:68278 | DOI:10.1038/ng1894
2005
Shore P. (2005). A role for Runx2 in normal mammary gland and breast cancer bone metastasis.Journal of cellular biochemistry, 96(3), 484-9. eScholarID:1c5347 | PMID:16052475 | DOI:10.1002/jcb.20557
Inman CK, Li N, Shore P. (2005). Oct-1 counteracts autoinhibition of Runx2 DNA binding to form a novel Runx2/Oct-1 complex on the promoter of the mammary gland-specific gene beta-casein.Molecular and cellular biology, 25(8), 3182-93. eScholarID:1c5346 | PMID:15798204 | DOI:10.1128/MCB.25.8.3182-3193.2005
2003
Inman CK, Shore P. (2003). The osteoblast transcription factor Runx2 is expressed in mammary epithelial cells and mediates osteopontin expression. J Biol Chem, 278(49), 48684-9. eScholarID:1c1912 | PMID:14506237 | DOI:10.1074/jbc.M308001200
Bristow CA, Shore P. (2003). Transcriptional regulation of the human MIP-1alpha promoter by RUNX1 and MOZ. Nucleic acids research, 31(11), 2735-44. eScholarID:1c1913 | PMID:12771199 | DOI:10.1093/nar/gkg401
2002
Shore P, Dietrich W, Corcoran LM. (2002). Oct-2 regulates CD36 gene expression via a consensus octamer, which excludes the co-activator OBF-1. Nucleic acids research, 30(8), 1767-73. eScholarID:1c1914 | PMID:11937630 | DOI:10.1093/nar/30.8.1767
2001
Bouillet P, Zhang LC, Huang DC, Webb GC, Bottema CD, Shore P, Eyre HJ, Sutherland GR, Adams JM. (2001). Gene structure alternative splicing, and chromosomal localization of pro-apoptotic Bcl-2 relative Bim. Mammalian genome : official journal of the International Mammalian Genome Society, 12(2), 163-8. eScholarID:1c3435 | PMID:11210187 | DOI:10.1007/s003350010242
2000
Shore P. and Sharrocks A.D. (2000). Regulation of Transcription by Extracellular Signals. In J. Locker (Ed.), Transcription Factors. (pp. 10). Bios Scientific Ltd. eScholarID:3c250
Corcoran, LM and SHORE P. (2000). Transcription Factors in B-Cell Development and Function. The Immunologist, 8, 11-13. eScholarID:1c6589
1999
Yang SH, Shore P, Willingham N, Lakey JH, Sharrocks AD. (1999). The mechanism of phosphorylation-inducible activation of the ETS-domain transcription factor Elk-1. The EMBO journal, 18(20), 5666-74. eScholarID:1c3436 | PMID:10523309 | DOI:10.1093/emboj/18.20.5666
1997
West AG, Shore P, Sharrocks AD. (1997). DNA binding by MADS-box transcription factors: a molecular mechanism for differential DNA bending. Molecular and cellular biology, 17(5), 2876-87. eScholarID:1c3437 | PMID:9111360
1996
Shore P, Whitmarsh AJ, Bhaskaran R, Davis RJ, Waltho JP, Sharrocks AD. (1996). Determinants of DNA-binding specificity of ETS-domain transcription factors. Molecular and cellular biology, 16(7), 3338-49. eScholarID:1c3438 | PMID:8668149
1995
Shore P, Sharrocks AD. (1995). The ETS-domain transcription factors Elk-1 and SAP-1 exhibit differential DNA binding specificities. Nucleic acids research, 23(22), 4698-706. eScholarID:1c3439 | PMID:8524663 | DOI:10.1093/nar/23.22.4698
Whitmarsh AJ, Shore P, Sharrocks AD, Davis RJ. (1995). Integration of MAP kinase signal transduction pathways at the serum response element. Science, 269(5222), 403-7. eScholarID:1c3440 | PMID:7618106 | DOI:10.1126/science.7618106
Sharrocks AD, Shore P. (1995). DNA bending in the ternary nucleoprotein complex at the c-fos promoter. Nucleic acids research, 23(13), 2442-9. eScholarID:1c3441 | PMID:7630721 | DOI:10.1093/nar/23.13.2442
Shore P, Sharrocks AD. (1995). The MADS-box family of transcription factors. European journal of biochemistry / FEBS, 229(1), 1-13. eScholarID:1c3442 | PMID:7744019 | DOI:10.1111/j.1432-1033.1995.tb20430.x
Shore P, Bisset L, Lakey J, Waltho JP, Virden R, Sharrocks AD. (1995). Characterization of the Elk-1 ETS DNA-binding domain. Journal of Biological Chemistry, 270(11), 5805-11. eScholarID:1c3443 | PMID:7890710
Shore P., Sharrocks A.D. Turning On Genes. Trends in Biochemical Sciences, 20, 7, 257-293 1995.
1994
Shore P, Sharrocks AD. (1994). The transcription factors Elk-1 and serum response factor interact by direct protein-protein contacts mediated by a short region of Elk-1. Molecular and cellular biology, 14(5), 3283-91. eScholarID:1c3444 PMID:8164681
Hornby DP, Whitmarsh A, Pinarbasi H, Kelly SM, Price NC, Shore P, Baldwin GS, Waltho J. (1994). The DNA recognition subunit of a DNA methyltransferase is predominantly a molten globule in the absence of DNA. FEBS letters, 355(1), 57-60. eScholarID:1c5753 | PMID:7957963 | DOI:10.1016/0014-5793(94)01171-0
1992
D Hornby, K Ford, P Shore. Purification of DNA Binding Proteins by Affinity and Ion Exchange Chromatography. Practical Protein Chromatography, 273-286. (1992)